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SGLT-2 is extensively expressed throughout the CNS, and c-Fos expression was also observed within 2 hours of administration of SGLT-2is in mice

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Cytokine-targeted nanoparticles: Nanoparticles can be engineered to specifically target and counteract crucial inflammatory cytokines implicated in the development of psoriasis, such as TNF- and IL-17

Endocrinology 151 , 14731486 (2010)