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Iron and Alzheimer's disease: from pathogenesis to therapeutic implications
GSTP1-775 knockdown cells (A2780/GSTP1) were therefore selected for use in additional experiments, following additional confirmation of increased total cellular glutathione levels (A2780 83.161.67 M and A2780/GSTP1 116.854.67 M), consistent with reduced GSTP1 catalytic activity
iNOS and ROS induce oxidative stress, leading to T cell apoptosis and the inhibition of T cell receptor (TCR) signaling [15]
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