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First developed in the 1980s by researchers at the University of Arizona, Melanotan is principally used for the treatment of skin disorders including vitiligo and erythropoietic protoporphyria that affect skin appearance and sensitivity (especially to sunlight)

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Root topography by scanning electron micrography Fresh root segments (1 cm) from each treatment were fixed with 1 M PBS (pH 7.3) containing 2.5% (w/v) glutaraldehyde for 1 day