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Under pathological conditions, they may initially exert neuroprotective effects, yet prolonged activation often results in metabolic disturbances and neurotoxic gliotransmission, highlighting their dual role in CNS pathology and their potential in therapy [293]

[84] Vitamin D, Possible Key to MS Geographical Distribution: One factor that correlates with MS is latitude

Another important finding of this study was that exenatide was also found to abolish the harmful effects of ritonavir (GLUT4 antagonist) on survival [52]

Thomson DW, Dinger ME