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In PCOS, oxidative stress contributes to: Hormonal disruption Insulin resistance Inflammation Poor skin recovery Pigmentation flare-ups Glutathione helps by: Reducing free radical damage Supporting cellular repair Calming stress-driven melanin activity This is why skin issues in PCOS often improve after internal balance improves , not before

Multiparameter flow cytometry

Next, treated SPZs were diluted in DMEM 3% BSA and added to the 3SP2 coated Lab-Tek wells (~30 000 SPZs/well) and allowed to glide for 1h at 37C

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