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HFSCs are located in the bulge region and the inner and outer root sheaths at the junction of the arrector pili muscle and the hair follicle, and they are involved in the periodic regeneration of hair follicles (Zhang and Chen, 2024)

2 A ) are supported by consensus guidelines (2224), supporting the utility of this approach for assessing real-world evidence of therapies and identifying promising candidates for clinical trials

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Escalation of Care: if individual glycemic (blood sugar targets are not reached with first-line therapies, the guide suggests adding: DPP-4 inhibitors Sulfonylureas Pioglitazone Insulin-based treatments