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Modulation of anxiety-like behavior in galactooligosaccharide-fed mice: a potential role for bacterial tryptophan metabolites and reduced microglial reactivity

GLP-1 medications support the bodys natural appetite and blood sugar regulation systems

These drugs have caused a revolution in the diabetes and weight loss arenas not only due to their success, but also because of their cost

After adding bFGF and EGF to culture medium, mural cells expressed aSMA and SMA-22 but not NG2+ and PDGFR (Wang et al., 2012)

These are on-target effects -- the same receptor activation that suppresses appetite and lowers blood glucose also causes GI symptoms