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Long-term LAC can significantly reduce the GABA level in the hippocampus of mice, but the GABA level in the cortex did not change significantly (103)

Those aren't theoretical differences

7 , S637S640 (2016)

A 2025 paper published in Frontiers in Pharmacology investigated the effect of GHK-Cu in an experimental colitis model

Ohkama-Ohtsu N et al (2008) A gamma-glutamyl transpeptidase-independent pathway of glutathione catabolism to glutamate via 5-oxoproline in Arabidopsis