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Similarly, post-mortem studies in long-standing PD cases reveal capillary damage and fragmentation in cortical areas and in brainstem regions, as well as increased endothelial cell nuclei in substantia nigra [153,154]

Combination incretinamylin strategies: Trials combining Cagrilintide with GLP1 analogues (e.g., semaglutide, in CagriSema constructs) demonstrate synergistic weight loss and improved glycemic control compared to either agent alone