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Results Metabolite profiling in the motor cortex with TDP-43 pathology reveals energy deficiency and oxidative stress We previously identified major mitochondrial problems, especially within the corticospinal motor neurons (CSMN) of prpTDP-43 A315T mice 16 (Fig

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Vitamin D deficiency can stimulate cell proliferation and leiomyoma growth [61]

Pharmacological management Pharmacological treatment has focused on prokinetic medications, but, as discussed, it is now appreciated that the relationship between symptomatic improvement and acceleration of gastric emptying is, at best, modest [68]

Furthermore, organizations such as the American Diabetes Association emphasize individualized care plans that consider multiple therapeutic endpoints