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Effect of semaglutide on cardiac structure and function in patients with obesity-related heart failure

More recently, it has petitioned the FDA to block production of compounded semaglutide by placing the ingredient on the Demonstrable Difficulties for Compounding list, which excludes drugs that are too difficult to compound safely

After screening the abstracts of the articles retrieved, 2 of the authors (DMC and JPC) performed a full-text review to select relevant articles

This suggests both peptides have acceptable tolerability profiles for most users, though individual responses vary widely