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Hesperidin (Matias et al., 2017), rutin (Omar et al., 2017) can reduce the amount of free Ca 2+ located between brain cells when fighting against neurogenic excitotoxicity and can attenuate the decrease of the mitochondrial membrane potential and increase caspase-3 activity (Lutz et al., 2015)

[DOI] [PubMed] [Google Scholar] 35.N-acetylcysteine for polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled clinical trials

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The Gupta 2022 meta-analysis specifically found that longer treatment duration was positively associated with better outcomes

Avoid taking in case of known allergy to any of the ingredients in the product