Carnitine has been recognized as a nutritional supplement in cardiovascular disease and there is increasing evidence that carnitine supplementation may be beneficial in treating obesity, improving glucose intolerance and total energy expenditure
Although not approved for clinical use by regulatory authorities like the FDA in the United States and TGA in Australia, Melanotan 2 tanning nasal spray remains a significant interest in various preclinical studies aiming to improve understanding and therapeutic intervention in these areas
Summary & Expert Recommendation L-Carnitine helps your body use fat for energy and can support workout days and recovery, without stimulants
Rare but serious adverse effects including pancreatitis, gallbladder disease, and acute kidney injury (usually secondary to dehydration from vomiting) remain possible
Tesamorelin, a more potent GHRH analog, has Phase 3 human trial data for visceral fat reduction in HIV-associated lipodystrophy, which provides some mechanistic validation for the class