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Naive male mice subjected to intraperitoneal KYN treatment, the product of IDO, also produces depressive-like behavior in a dose-dependent manner [114], potentially because high levels of KYN would lead to a build-up of downstream metabolites like 3-HK
Jog E, Jainarayanan AK, La Ferlita A, Chakraborty A, Dalwai A, Yahya S, et al
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