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10.1007/s13346-018-00613-y [DOI] [PubMed] 15.Parry Strong A, Haeusler S, Weatherall M, Krebs J (2016) Sublingual vitamin B12 compared to intramuscular injection in patients with type 2 diabetes treated with metformin: a randomized trial

Commonly reported issues include mild gastrointestinal discomfort, particularly when starting the compound, and temporary headaches during the adjustment period

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0.25mg dose: Draw to 7.5 units (round to 7 or 8) 0.5mg dose: Draw to 15 units 1.0mg dose: Draw to 30 units 1.7mg dose: Draw to 51 units 2.0mg dose: Draw to 60 units 2.4mg dose: Draw to 72 units These unit measurements are easier to read on a standard insulin syringe, which is why the 3mL reconstitution has become the default recommendation across most research communities