However, higher doses can reduce the effects caused by oxidative stress and inflammation in COPD, demonstrating a positive impact on the rate of exacerbation [117]
Most notably, these studies are limited by healthy user bias where women who use HRT have systematically different characteristics (eg, socioeconomic status) than those who do not, which may be sources of residual confounding and therefore may influence some of the seemingly beneficial reported outcomes of HRT (134)
But you're confused about whether peptides are safe during perimenopause, if they'll interfere with remaining hormones, and which specific peptide addresses the worst symptoms you're experiencing
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All authors have given approval to the final version of the manuscript