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Historically, the brain has been considered an immune-privileged organ that is shielded from peripheral immune interactions by the bloodbrain barrier (BBB) [6]

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PMID: 32858949 Tomas FM, Knowles SE, Owens PC, Read LC, Chandler CS, Gargosky SE, Ballard FJ

Peptides function by signaling and regulating biological processes, whereas steroids act through hormone pathways that influence metabolism, inflammation, and muscle growth