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The mechanism may involve modulation of somatostatin (GH inhibitory hormone) release from the hypothalamus, or interaction with GHRH neurons

Notes: Rotate injection sites after each injection

The application of liposomal azelaic acid, 4-n butyl resorcinol and retinol serum enhanced by microneedling for treatment of malar pattern melasma: a case series

It is not an FDA-approved drug and not a legal over-the-counter supplement