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Body fat percentage Same BMI, 2x body fat

Reports of persistent craving, emotional eating, binge-like eating, or continued intake of highly palatable foods may indicate that motivational or affective eating pathways remain active despite pharmacological enhancement of satiety (94)

Wiviott et al, 2019), whilst in the ertugliflozin CVOT the advantage over placebo showed a strong trend that just fell short of significance (Cannon et al, 2020)

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