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Similar content being viewed by others Introduction Research programs investigating weight-loss interventions are currently based almost exclusively on randomized clinical trials (RCTs) to ascertain the efficacy and safety of a treatment

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In the study, participants followed a diet and exercise program, which is a requirement when taking semaglutide for weight loss

GLP-1 receptor agonists stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning they promote insulin release only when blood glucose levels are elevated

Cholecystitis was reported by 0.6% of Wegovy patients and 0.2% of placebo patients