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Glutathione deficiency increases susceptibility to oxidative stress, which may be the underlying cause of many diseases including cancer, heart disease, Parkinsons, and Alzheimers [8]

It was subsequently agreed that the consensus statement would address the role of oral NAC across, eight common respiratory conditions, namely: stable COPD to prevent exacerbations, during an acute exacerbation of COPD (AECOPD), tuberculosis (TB) and anti-tubercular drug-induced liver injury (AT-DILI), non-cystic fibrosis bronchiectasis, cystic fibrosis, lung infections, interstitial lung disease (ILD), and asthma

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Therefore, stronger basicity is suggested by lower pKb values, remaining consistent with the inverse relationship noted above