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Why Weight Regain Occurs : Biological adaptations that promoted weight gain initially remain present Appetite and food preoccupation often return when medication stopped Metabolic rate may decrease during weight loss (adaptive thermogenesis) Hormonal changes that defend against weight loss persist Long-Term Management : Most individuals require ongoing medication for sustained weight loss maintenance This is similar to other chronic disease treatments (e.g., blood pressure medications) Obesity is a chronic disease requiring long-term management Strong lifestyle habits help minimize regain but may not prevent it entirely Discuss any plans to discontinue medication with healthcare provider to develop appropriate tapering plan and maintenance strategies

For many people, this means their body is no longer as efficient at holding onto heat, making them more sensitive to air conditioning, wind, or even slight drops in evening temperatures

He founded the Metabolic Solutions Institute and its nonprofit arm, dedicated to advancing mental health science

The user applies the medication instead of using creams or lotions

This year, OPM allowed FEHB plans to begin offering Part D coverage to Medicare-eligible enrollees