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Under unfolded protein stress conditions, GRP78 binds to unfolded or misfolded proteins and subsequently activates downstream ER stress sensors, including IRE1, PERK, and ATF6, to trigger a response to unfolded proteins (Yoboue et al., 2017) , (Wei et al., 2012)

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Alpha-lipoic acid (ALA) directly recycles and extends the metabolic life spans of vitamin C, glutathione, and coenzyme Q10, necessary for glutathione recycling

[DOI] [PMC free article] [PubMed] [Google Scholar] 222.Jodeleit H, Al-Amodi O, Caesar J, Villarroel Aguilera C, Holdt L, Gropp R, Beigel F, Siebeck M

Wilton-Clark, H