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LA maintains the cellular antioxidant state indirectly through activating the NRF2 pathway, and the NRF2 pathway governs the expression of antioxidant genes (such as -glutamylcysteine synthetase (-GCL), NAD(P)H quinone oxidoreductase 1 (NQO-1), and superoxide dismutase (SOD)) for enhancing the cell's antioxidant capacity and anti-inflammatory response [34, 35]

Peptide stability and potential degradation pathways

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Reduced Intestinal Inflammation How it works: It lowers pro-inflammatory markers in the gut, helping conditions like Crohns disease and ulcerative colitis

At 10 active days per cycle, the total annual injection commitment at maximum frequency is only 30 days, making it one of the lowest-burden protocols in terms of active treatment time