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[7] That preclinical promise carried the compound into a human Phase II program for postoperative ileus but the randomized, placebo-controlled trial in bowel-resection patients did not meet its primary efficacy endpoint, and clinical development was subsequently discontinued

In the future, studies that fully understand the molecular mechanism underlying HT disease will significantly contribute to the diagnosis and therapy while controlling course of disease

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Histological analysis of hypoglycemic agents on liver fibrosis in patients with non-alcoholic fatty liver disease: a systematic review