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for more details, see Sampson et al., 2021 13

When in doubt, start with a reduced dose to assess response before committing to a full protocol

If youre using a stove, its safer to refrigerate the broth overnight and restart the process in the morning by bringing it back to a boil, then reducing it to a simmer

As an example, GSTs protect cellular DNA against oxidative damage that can lead to an increase of DNA mutations or induce DNA damage promoting carcinogenesis 9