These subtypes, comprising enterocytes, Paneth cells, goblet cells, tuft cells, M cells, and EECs (6), fulfill specialized functions, with absorptive enterocytes and secretory (mucin-producing) goblet and (antimicrobial peptides-producing) Paneth cells accounting for the largest proportion of IECs
GLP-1 receptor agonists should only be continued if there is an adequate response, defined as a reduction of at least 11 mmol/mol (1.0%) in HbA1c and a weight loss of at least 3% of initial body weight at six months
While pharmaceutical options are still being researched, foundational cellular support remains a cornerstone of functional recovery
These are typically mild and often resolve after the first several weeks of treatment
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