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Benefits of metformin in attenuating the hallmarks of aging

While GHSR is primarily active in the brain, it is also found in other tissues such as the gastrointestinal tract, heart, lungs, liver, kidneys, pancreas, fat tissue, and immune cells

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These effects can lead to lower blood pressure, improved cholesterol levels, and reduced strain on the heart, which support overall cardiometabolic health

To better evaluate this correlation and explore the potential therapeutic role of vitamin C, further large-scale data are needed on skin levels of vitamin C in patients with moderate and severe AD