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[39] [40] RSSR' + 2 GSH RSH + R'SH + GSSG where R and R' are parts of the micro-nanogel structure, and GSSG is oxidized glutathione (glutathione disulfide)

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Studies have shown that genistein can increase GSH levels and GPX activity along with decreased oxidative stress in diabetic cardiomyopathy and DOX-mediated cardiomyopathy [132, 133]