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The trial involved 2 phases
As GLP-1 has been implicated as a mediator in the putative gutrenal axis (a rapid-acting feed-forward loop that regulates postprandial fluid and electrolyte homeostasis), direct actions on the kidney have been proposed
The drug has taken over the cultural zeitgeist in the last year, with everyone from actors, producers, TV presenters and TikTok users singing its praises
In a one-year follow-up study, elevated serum MDA levels were identified as independent predictors of mortality in CAD patients, supporting the hypothesis that lipid peroxidation contributes to both the development and severity of heart disease (57)