HCV replication is hampered by the induction of ferroptosis in host cells via FADS2 activation (Yamane et al., 2022)
While the protection of normal cells against radiation-induced cell death by ebselen has been attributed to its ability to detoxify cellular/mitochondrial ROS through the GPx mechanism, the molecular mechanism contributing to its radio-sensitization effect in cancer cells is still not fully understood
doi: 10.1038/s41586-018-0023-4 381 WheelerM
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The body composition substudy The Lancet Diabetes and Endocrinology published a substudy specifically examining body composition changes using DXA scanning, the gold standard for measuring fat versus lean mass