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Consequently, maintaining the therapeutic effects of GLP-1R agonism requires a long-term dosing regimen, much like medications used for other chronic conditions, such as statins for cholesterol control, ACE inhibitors and beta-blockers for blood pressure, or warfarin for blood thinning

Cost remains a barrier with a persons income being a major factor in determining compliance with GLP1-RAs (Rodriguez et al., 2025)

Eli Lilly is the only official manufacturer of tirzepatide

Autoimmune and inflammatory conditions Patients with autoimmune conditions including lupus, rheumatoid arthritis, and Hashimoto thyroiditis have increasing access to GLP-1 therapy, and the anti-inflammatory mechanism provides specific rationale for this use