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(2003) Urinary and plasma homocysteine and cysteine levels during prolonged oral N-acetylcysteine therapy

Dans un essai clinique multicentrique europen, la supplmentation en L-carnitine (sous forme de propionyl L-carnitine 2 g/jour pendant 12 mois) chez des patients atteints de claudication modre svre a permis d'obtenir une amlioration significative en termes de distance maximale parcourue et de qualit de vie perue par rapport aux patients recevant uniquement des placebos

So unless its being used up in 1-2 days max, you should not add water to it