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Amino Acid Sequence Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH Key Structural Modifications Norleucine (Nle) substitution to reduce oxidative degradation D-Phenylalanine (D-Phe) to improve receptor interaction N-terminal acetylation and C-terminal amidation to enhance stability Molecular Formula: CHNO Molecular Weight: 1646.874 g/mol CAS Number: 75921-69-6 Sequence: Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH What Does Scientific Research Examine About MT-1

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The first formal Phase I human study of cyclic MT-II was reported by Dorr, Lines, Levine, Brooks, Xiang, Hruby, and Hadley in Life Sciences 1996 in three male research subjects at the University of Arizona [5]

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