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"A well-nourished mama is better equipped to handle the challenges of nursing

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M1 secretes pro-inflammatory cytokines (mainly IL-1, IL-6, and TNF), which lead to osteoclast (OC) activation and joint erosion, and M2 produces anti-inflammatory cytokines such as IL-10 and transforming growth factor- (TGF-) to promote angiogenesis and tissue remodeling [82, 83]