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This review summarizes CHE as a multi-organ syndrome, focusing on the gut-liver-muscle-brain axis, diagnosis, treatment, and future challenges and directions for clinical implementation

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Discussion To the best of our knowledge, this is the first study to demonstrate that dual-mode laser therapytargeting both pigment and vascular components of melasmais safe and more effective across multiple clinical parameters compared with single-mode treatment targeting only pigmentation

Elsevier, Amsterdam, pp 7997 Taylor A, Foo SS, Bruzzone R et al (2015) Fc receptors in antibody-dependent enhancement of viral infections