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The study cohort, comprising 1,145 patients from multiple international sites, showed that semaglutide consistently improved KCCQ-CSS across all diuretic subgroups, with a more pronounced effect observed in patients using loop diuretics

(2023) study in the New England Journal of Medicine remains the primary reference for retatrutide dosage in the context of weight management

They typically had shorter duration of obesity before treatment

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Control of food intake by gastrointestinal peptides: mechanisms of action and possible modulation in the treatment of obesity