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Additionally, prebiotics promote immune modulation and enhance gut barrier integrity by shaping the gut microbiota composition towards a more beneficial profile (141)

This upregulation will in turn up-regulate at the transcriptional level the expression of proinflammatory cytokines (IL-1, IL-6, IL-18, etc.), chemokines, adhesion molecules, Fas ligands33 which will activate the caspase cascades (apoptosis) and the ATP depletion from mitochondria (necrosis) leading to an autosustaining and autopotentiating oxidative loop

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If you have severe or persistent skin concerns, please visit a board-certified dermatologist for a personalized treatment plan