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However, GEP44 has a superior therapeutic window, as rats could be treated with higher doses (up to 100 nmol/Kg/d) with no notable adverse effects

A drug that can reliably reactivate dormant follicles would validate an approach that could eventually be applied to other aging-related conditions

Both are effective, but they act in slightly different ways

The standard protocol starts at 2.5 mg weekly with gradual escalation every four weeks based on response and tolerability, regardless of gallbladder status

These trials aim to assess the safety, pharmacokinetics, and anti-tumor efficacy of CCS1477 both as monotherapy and in combination with standard chemotherapeutics or immunomodulators