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However, kidney damage primarily occurs in people who are already having kidney problems or those taking diuretic medications that get rid of excess water

Often, side effects can be managed by adjusting the dosage, changing the timing of the medication, or adding supportive treatments like anti-nausea medications

These practices align with what the mechanism would predict as protective

In preclinical research, SLU-PP-332 is primarily investigated for its ability to activate ERR-mediated transcription, leading to increased expression of genes involved in mitochondrial biogenesis, oxidative phosphorylation, and cellular energy metabolism

Part of the explanation may be where the study appeared