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Clinical trials have documented that nausea, diarrhea, vomiting, constipation, dyspepsia, eructation (belching), and abdominal discomfort occur frequently, particularly during dose initiation and escalation

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Tirzepatide: Stands out for its dual agonism (GLP-1 and GIP receptors), resulting in substantial weight loss in addition to glycemic control

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Your body can only absorb about 200-300 mL of water per 15-minute period, so chugging a liter will just send most of it to your bladder