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Metab Brain Dis 28(2):155159

Full physical activity typically resumes at six to eight weeks post-surgery

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not more than once in 24 hours Onset: Effects typically begin within 3045 minutes Duration: Effects can last 612 hours Nausea mitigation strategies used in practice: Eat a low-fat meal approximately 1 hour before injection Consider prophylactic ondansetron (Zofran) 4 mg 30 minutes before, if nausea was problematic on prior doses Starting at 1 mg for the first dose to establish individual tolerance PT-141 is available by prescription only as Vyleesi (the brand-name autoinjector)