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Zepbound recorded 615,300 total prescriptions and 350,600 new prescriptions, compared with 632,500 and 346,400 in the prior week, indicating a slight decline in overall volumes but continued growth in new starts

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doi: 10.1016/j.celrep.2023.113295 58 GuoMZhuangYWuYZhangCChengXXuDet al

the reduced distal sodium delivery is associated with relative activation of the RAAS, which together with the physiological post-feeding rising in insulin levels promote distal sodium reabsorption by activating the Na/K pump in the distal tubule (Fig