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JDD and BY synthesised, characterised and provided the GLP1-E2 compound and gave scientific input on its use
Mitochondrial peptides modulate mitochondrial function during cellular senescence
For mitochondria analysis, cells were washed twice in RPMI media (no FBS) loaded with 10 nmol ml 1 Mitotracker Green (Thermo Fisher Scientific), 25 nmol ml 1 TMRM (Thermo Fisher Scientific), or 5 mmol ml 1 MitoSox Red for 20 min at 37 C in RPMI (no FBS)
1987Feb;62:123127
Further, the impact of GLP-1R agonists on cancer outcomes may vary significantly based on patient age and sex, emphasizing the need to consider age- and sex-specific factors in evaluating their therapeutic use
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