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They reported that 159 genes had p -values G mutation and increased expression of LARS2 gene in the brains of patients with bipolar disorder and schizophrenia

Environ Health Perspect 125

On the other hand, AR also utilizes NADPH to convert glucose to sorbitol, which depletes intracellular NADPH, making GSSG irreducible and promoting oxidative stress 18

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Walker ER, McGee RE, Druss BG