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Nature 526, 666671

3.3 Glutaminase inhibition affects mitochondrial respiration and energy metabolism in CLL cell lines but can be successfully compensated for by glycolysis In the HG-3 and MEC-1 cell lines, CB-839 treatment caused dose-dependent decreases in the OCR, including the basal OCR, maximal respiration rate, and spare respiratory capacity

They help maintain a balance in the gut microbiota, ensuring proper production of glutathione in the intestines

These results strongly suggested that cPKC acted as the upstream kinase of GSTP to phosphorylate Ser184 of GSTP in macrophages

HBOT also induce neurogenesis of endogenous neural stems cells suggesting its beneficial role against neurodegeneration