Grading and staging the histopathological lesions of chronic hepatitis: the Knodell histology activity index and beyond Hepatology
This is due to its ability to regulate the expression of many molecular targets such as VEGF-A/VEGFR2 pathway, p38MAPK/ERK-1/2/PI3K/protein kinase B (AKT), HIF-1, IL-1, IL-2, IL-6, IL-8, IL-10, IL-17A, IL-18, IL-33, TNF-, NF-kB, IFN-, IGF-1-induced activation of IGF-1R, ER-, and ER- receptors, miR-95, miR-103, miRNA-138, miRNA-155, miR-183, miR-223, MMP-1, MMP-2, MMP-3, MMP-9, lncRNA-MEG3, lncRNA-H19, Ang-1 mRNA, Ang-2 mRNA, mRNA of urokinase plasminogen activator, mRNA expression and secretion of leptin, CD31, Tie-2, MCP-1 mRNA and protein, HGF, Nrf2, HO1, Keap1, COX-2, PGE-2, MKNK1, and human DNA TOP3A
Journal of Ophthalmology, 2015:1-13
Note one recurring literature trap: the dimer (CKPV) is a chemically different molecule with its own clinical record, and results attributed to it do not transfer to bare KPV, on which no human trials exist
Many stimulate your body to produce growth hormone, but some dont