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Vitamin C also plays an important role in collagen production, which affects the integrity of skin, blood vessels, cartilage, and connective tissues

Planta 236:765779 Pignocchi C, Kiddle G, Hernndez I, Foster SJ, Asensi A, Taybi T, Barnes J, Foyer CH (2006) Ascorbate oxidase-dependent changes in the redox state of the apoplast modulate gene transcript accumulation leading to modified hormone signaling and orchestration of defense processes in tobacco

Melanocytes in the skin have more accessible iron than keratinocytes

It is proven that IFN- secreted by Th1 can block Th17 development ( + Tregs inhibit the activation and proliferation of autoreactive T cells through direct contact or the secretion of inhibitory cytokines such as IL-10 and TGF-

This forces astrocytes to rely more on glycolysis for energy, contributing to metabolic reprogramming (Liddelow et al., 2017