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For patients with a history of cardiovascular events without heart failure, metformin, SGLT2 inhibitors, or GLP-1 RAs are recommended as first-line and DPP4 inhibitors, pioglitazone, acarbose, or insulin as second-line treatment [5]

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Incretins stimulate pancreatic -cell proliferation and insulin secretion, delay gastric emptying and act centrally to suppress appetite

CLICK HERE TO GET THE FOX NEWS APP When contacted by Fox News Digital regarding the potential for overdoses, Novo Nordisk, maker of Ozempic and Wegovy, provided a statement