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(147) found that a one-month IF regimen, initiated 3 days post-TBI, enhanced the proliferation of hippocampal subgranular zone neural stem cells, increased neuropeptide Y (NPY) expression in the hippocampus, and improved cognitive performance in the Morris water maze test

It plays a key role in conditions like asthma and autoimmune diseases

Skin-related benefits typically take longer to become apparent, often requiring 4-8 weeks of regular supplementation combined with a balanced diet and proper skincare routine

It became popular in the injury-recovery world because preclinical studies suggest it may support tissue repair, particularly in tendons, ligaments, and muscle

This is highlighted by evidence in the literature indicating that NRF2 can play both a protective and pathogenic role depending on the timing and duration of activation (48)